| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Alpha-actinin-1 and Alpha-actinin-2 and Alpha-actinin-3 and Alpha-actinin-4 (21-70 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACTN2ACTN3888981ACTN2_HUMANACTN3_HUMANACTN4_HUMAN |
| Immunogen Region: | 21-70 aa |
| Specificity: | Actinin-Alpha 1/2/3/4 Polyclonal Antibody detects endogenous levels of Actinin-Alpha 1/2/3/4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ACTN1/2/3/4 at the amino acid range 21-70 |
| Protein Name | Alpha-Actinin-1Alpha-Actinin Cytoskeletal IsoformF-Actin Cross-Linking ProteinNon-Muscle Alpha-Actinin-1 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-3000170Reactome: R-HSA-373753Reactome: R-HSA-446388 |
| Cellular Localisation | CytoplasmCytoskeletonMyofibrilSarcomereZ LineCell MembraneCell JunctionCell ProjectionRuffleColocalizes With Myoz2 And Ppp3ca At The Z-Line Of Heart And Skeletal MuscleColocalizes With Psd In Membrane Ruffles And Central Reticular Structures |
| Alternative Antibody Names | Anti-Alpha-Actinin-1 antibodyAnti-Alpha-Actinin Cytoskeletal Isoform antibodyAnti-F-Actin Cross-Linking Protein antibodyAnti-Non-Muscle Alpha-Actinin-1 antibodyAnti-ACTN1 antibody |
Information sourced from Uniprot.org