Western blot analysis of MOUSE-HEARTmouse brainusing Acetyl-TAL1/2 (K221/K222/K36/K37) antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Anti-Acetyl-TAL1-Lys37 antibody (STJ97700)

SKU:
STJ97700
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Acetyl-T-cell acute lymphocytic leukemia protein 1-Lys37 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TAL1
Gene ID: 6886
Uniprot ID: TAL1_HUMAN
Specificity: Acetyl-TAL1/2 (K221/K222/K36/K37) Polyclonal Antibody detects endogenous levels of TAL1/2 around the acetylation site of K221 protein.
Immunogen: Synthesized acetyl-peptide derived from the human TAL1/2 around the acetylation site of K221.
Post Translational Modifications Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia. Ubiquitinated.subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.
Function Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
Protein Name T-Cell Acute Lymphocytic Leukemia Protein 1
Tal-1
Class A Basic Helix-Loop-Helix Protein 17
Bhlha17
Stem Cell Protein
T-Cell Leukemia/Lymphoma Protein 5
Database Links Reactome: R-HSA-8939236
Reactome: R-HSA-9616222
Cellular Localisation Nucleus
Alternative Antibody Names Anti-T-Cell Acute Lymphocytic Leukemia Protein 1 antibody
Anti-Tal-1 antibody
Anti-Class A Basic Helix-Loop-Helix Protein 17 antibody
Anti-Bhlha17 antibody
Anti-Stem Cell Protein antibody
Anti-T-Cell Leukemia/Lymphoma Protein 5 antibody
Anti-TAL1 antibody
Anti-BHLHA17 antibody
Anti-SCL antibody
Anti-TCL5 antibody

Information sourced from Uniprot.org

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