Anti-ACBD3 antibody (1-160) (STJ118995)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACBD3 (1-160) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACBD3 |
| Gene ID | 64746 |
| Uniprot ID | GCP60_HUMAN |
| Immunogen Region | 1-160 |
| Immunogen Sequence | MAAVLNAERLEVSVDGLTLS PDPEERPGAEGAPLLPPPLP PPSPPGSGRGPGASGEQPEP GEAAAGGAAEEARRLEQRWG FGLEELYGLALRFFKEKDGK AFHPTYEEKLKLVALHKQVL MGPYNPDTCPEVGFFDVLGN DRRREWAALGNMSKEDAMVE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ACBD3 (NP_073572.2). |
Additional Info
| Tissue Specificity | Ubiquitous, with highest expression in testis and ovary. |
| Function | Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. Recruits PI4KB to the Golgi apparatus membrane.enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. (Microbial infection) Plays an essential role in Aichi virus RNA replication by recruiting PI4KB at the viral replication sites. |
| Protein Name | Golgi Resident Protein Gcp60Acyl-Coa-Binding Domain-Containing Protein 3Golgi Complex-Associated Protein 1Gocap1Golgi Phosphoprotein 1Golph1Pbr- And Pka-Associated Protein 7Peripheral Benzodiazepine Receptor-Associated Protein Pap7 Cleaved Into - Golgi Resident Protein Gcp60 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideMitochondrionAlso Mitochondrial (Via Its Interaction With Pbr) |
| Alternative Antibody Names | Anti-Golgi Resident Protein Gcp60 antibodyAnti-Acyl-Coa-Binding Domain-Containing Protein 3 antibodyAnti-Golgi Complex-Associated Protein 1 antibodyAnti-Gocap1 antibodyAnti-Golgi Phosphoprotein 1 antibodyAnti-Golph1 antibodyAnti-Pbr- And Pka-Associated Protein 7 antibodyAnti-Peripheral Benzodiazepine Receptor-Associated Protein Pap7 Cleaved Into - Golgi Resident Protein Gcp60 - N-Terminally Processed antibodyAnti-ACBD3 antibodyAnti-GCP60 antibodyAnti-GOCAP1 antibodyAnti-GOLPH1 antibody |
Information sourced from Uniprot.org