Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Acetyl-CoA acetyltransferase, mitochondrial (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ACAT1 |
Gene ID: |
38 |
Uniprot ID: |
THIL_HUMAN |
Immunogen Region: |
221-270 aa |
Specificity: |
ACAT-1 Polyclonal Antibody detects endogenous levels of ACAT-1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ACAT1 at the amino acid range 221-270 |
Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. |
Protein Name | Acetyl-Coa Acetyltransferase - MitochondrialAcetoacetyl-Coa ThiolaseT2 |
Database Links | Reactome: R-HSA-70895Reactome: R-HSA-77108Reactome: R-HSA-77111Reactome: R-HSA-9837999Reactome: R-HSA-9854311 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-Acetyl-Coa Acetyltransferase - Mitochondrial antibodyAnti-Acetoacetyl-Coa Thiolase antibodyAnti-T2 antibodyAnti-ACAT1 antibodyAnti-ACAT antibodyAnti-MAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance