Anti-ACADVL antibody (1-140) (STJ110175)

Name: Anti-ACADVL antibody (1-140) (STJ110175)
SKU: STJ110175
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110175

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit polyclonal ACADVL (1-140) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ACADVL
Gene ID	37
Uniprot ID	ACADV_HUMAN
Immunogen Region	1-140
Immunogen Sequence	MQAARMAASLGRQLLRLGGG SSRLTALLGQPRPGPARRPY AGGAAQLALDKSDSHPSDAL TRKKPAKAESKSFAVGMFKG QLTTDQVFPYPSVLNEEQTQ FLKELVEPVSRFFEEVNDPA KNDALEMVEETTWQGLKELG
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ACADVL (NP_000009.1).

Tissue Specificity	Predominantly expressed in heart and skeletal muscle (at protein level). Also detected in kidney and liver (at protein level).
Post Translational Modifications	S-nitrosylation at Cys-237 in liver improves catalytic efficiency.
Function	Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains.
Protein Name	Very Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial Vlcad
Database Links	Reactome: R-HSA-381038 Reactome: R-HSA-77305
Cellular Localisation	Mitochondrion Inner Membrane Peripheral Membrane Protein Isoform 2: Mitochondrion Inner Membrane
Alternative Antibody Names	Anti-Very Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody Anti-Vlcad antibody Anti-ACADVL antibody Anti-VLCAD antibody

Information sourced from Uniprot.org