Anti-ACADSB antibody (133-432) (STJ117213)

Name: Anti-ACADSB antibody (133-432) (STJ117213)
SKU: STJ117213
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ117213

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Short Description	Rabbit polyclonal ACADSB (133-432) antibody for use in IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ACADSB
Gene ID	36
Uniprot ID	ACDSB_HUMAN
Immunogen Region	133-432
Immunogen Sequence	ASVAVFCEIQNTLINTLIRK HGTEEQKATYLPQLTTEKVG SFCLSEAGAGSDSFALKTRA DKEGDYYVLNGSKMWISSAE HAGLFLVMANVDPTIGYKGI TSFLVDRDTPGLHIGKPENK LGLRASSTCPLTFENVKVPE ANILGQIGHGYKYAIGSLNE GRIGIAAQMLGLAQGCFDYT IPYIKERIQFGKRLFDFQGL QHQVAHVATQLEAARLLTYN AARLLEAGKPFIKEASMAK
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human ACADSB (NP_001600.1).

Tissue Specificity	Ubiquitously expressed.
Function	Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug.
Protein Name	Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial Sbcad 2-Methyl Branched Chain Acyl-Coa Dehydrogenase 2-Mebcad 2-Methylbutyryl-Coenzyme A Dehydrogenase 2-Methylbutyryl-Coa Dehydrogenase
Database Links	Reactome: R-HSA-70895 Reactome: R-HSA-9837999
Cellular Localisation	Mitochondrion Matrix
Alternative Antibody Names	Anti-Short/Branched Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody Anti-Sbcad antibody Anti-2-Methyl Branched Chain Acyl-Coa Dehydrogenase antibody Anti-2-Mebcad antibody Anti-2-Methylbutyryl-Coenzyme A Dehydrogenase antibody Anti-2-Methylbutyryl-Coa Dehydrogenase antibody Anti-ACADSB antibody

Information sourced from Uniprot.org