Anti-ACAD9 antibody (1-270) (STJ110108)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACAD9 (1-270) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACAD9 |
| Gene ID | 28976 |
| Uniprot ID | ACAD9_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MSGCGLFLRTTAAARACRGL VVSTANRRLLRTSPPVRAFA KELFLGKIKKKEVFPFPEVS QDELNEINQFLGPVEKFFTE EVDSRKIDQEGKIPDETLEK LKSLGLFGLQVPEEYGGLGF SNTMYSRLGEIISMDGSITV TLAAHQAIGLKGIILAGTEE QKAKYLPKLASGEHIAAFCL TEPASGSDAASIRSRATLSE DKKHYILNGSKVWITNGGLA NIFTVFAKTEVVDSDGSVK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACAD9 (NP_054768.2). |
Additional Info
| Tissue Specificity | Ubiquitously expressed in most normal human tissues and cancer cell lines with high level of expression in heart, skeletal muscles, brain, kidney and liver. In the cerebellum uniquely expressed in the granular layer (at protein level). |
| Function | As part of the MCIA complex, primarily participates in the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphorylation. This moonlighting protein also has a dehydrogenase activity toward a broad range of substrates with greater specificity for long-chain unsaturated acyl-CoAs. However, in vivo, it does not seem to play a primary role in fatty acid oxidation. In addition, the function in complex I assembly is independent of the dehydrogenase activity of the protein. |
| Protein Name | Complex I Assembly Factor Acad9 - MitochondrialAcyl-Coa Dehydrogenase Family Member 9Acad-9 |
| Database Links | Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideEssentially Associated With Membranes |
| Alternative Antibody Names | Anti-Complex I Assembly Factor Acad9 - Mitochondrial antibodyAnti-Acyl-Coa Dehydrogenase Family Member 9 antibodyAnti-Acad-9 antibodyAnti-ACAD9 antibody |
Information sourced from Uniprot.org