Anti-ABO antibody (222-272 aa) (STJ193507)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human BGAT at the amino acid range 222-272
General Information
| Short Description | Rabbit polyclonal anti-Histo-blood group ABO system transferase (222-272 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABO |
| Gene ID | 28 |
| Uniprot ID | BGAT_HUMAN |
| Immunogen | Synthesized peptide derived from the human BGAT at the amino acid range 222-272 |
| Immunogen Region | 222-272 aa |
| Specificity | This antibody detects endogenous levels of BGAT at Human/Mouse |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group. |
| Protein Name | Histo-Blood Group Abo System TransferaseFucosylglycoprotein 3-Alpha-GalactosyltransferaseFucosylglycoprotein Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-GalactosyltransferaseHisto-Blood Group A TransferaseA TransferaseHisto-Blood Group B TransferaseB TransferaseNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Antibody Names | Anti-Histo-Blood Group Abo System Transferase antibodyAnti-Fucosylglycoprotein 3-Alpha-Galactosyltransferase antibodyAnti-Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase antibodyAnti-Histo-Blood Group A Transferase antibodyAnti-A Transferase antibodyAnti-Histo-Blood Group B Transferase antibodyAnti-B Transferase antibodyAnti-Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form antibodyAnti-ABO antibody |
Information sourced from Uniprot.org