| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ABI3 |
| Gene ID: | 51225 |
| Uniprot ID: | ABI3_HUMAN |
| Immunogen Region: | 197-366 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 197-366 of human ABI3 (NP_057512.2). |
| Immunogen Sequence: | VPDGRLSAASSAFSLASAGS AEGVGGAPTPKGQAAPPAPP LPSSLDPPPPPAAVEVFQRP PTLEELSPPPPDEELPLPLD LPPPPPLDGDELGLPPPPPG FGPDEPSWVPASYLEKVVTL YPYTSQKDNELSFSEGTVIC VTRRYSDGWCEGVSSEGTGF FPGNYVEPSC |
| Tissue Specificity | Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle. |
| Function | May inhibit tumor metastasis. In vitro, reduces cell motility. |
| Protein Name | Abi Gene Family Member 3New Molecule Including Sh3Nesh |
| Cellular Localisation | CytoplasmColocalizes With Pak2 At Leading Edge Of Cells |
| Alternative Antibody Names | Anti-Abi Gene Family Member 3 antibodyAnti-New Molecule Including Sh3 antibodyAnti-Nesh antibodyAnti-ABI3 antibodyAnti-NESH antibody |
Information sourced from Uniprot.org