| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ABHD6 |
| Gene ID: |
57406 |
| Uniprot ID: |
ABHD6_HUMAN |
| Immunogen Region: |
30-337 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-337 of human ABHD6. (NP_001307055.1). |
| Immunogen Sequence: |
WPSALIRIYYWYWRRTLGMQ VRYVHHEDYQFCYSFRGRPG HKPSILMLHGFSAHKDMWLS VVKFLPKNLHLVCVDMPGHE GTTRSSLDDLSIDGQVKRIH QFVECLKLNKKPFHLVGTSM GGQVAGVYAAYYPSDVSSLC LVCPAGLQYSTDNQFVQRLK ELQGSAAVEKIPLIPSTPEE MSEMLQLCSYVRFKVPQQIL QGLVDVRIPHNNFYRKLFLE IVSEKSRYSLHQNMDKIKV |
| Function | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting. |
| Protein Name | Monoacylglycerol Lipase Abhd62-Arachidonoylglycerol HydrolaseAbhydrolase Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-426048 |
| Cellular Localisation | Late Endosome MembraneSingle-Pass Type Ii Membrane ProteinLysosome MembraneMitochondrion Membrane |
| Alternative Antibody Names | Anti-Monoacylglycerol Lipase Abhd6 antibodyAnti-2-Arachidonoylglycerol Hydrolase antibodyAnti-Abhydrolase Domain-Containing Protein 6 antibodyAnti-ABHD6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
