| Host: |
Mouse |
| Applications: |
ICC/IHC-F/IHC-P/FC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-MRP2 is suitable for use in Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
M2III-6 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
PBS with 0.1% BSA and 0.02% sodium azide |
| Purification: |
Protein G purified |
| Concentration: |
100 ug/mL |
| Dilution Range: |
ICCIHC-F 1:20IHC-PFCWB 1:20-50 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
202-amino acid COOH terminal end of the protein. |
| Background | M2III-6 reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-6 was raised against a bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein. M2III-6 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
