Anti-ABCB10 antibody (300-400 aa) (STJ13100671)

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STJ13100671-100
€387.00
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Short Description :Rabbit polyclonal anti-ABCB10 (300-400 aa) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB (recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:Abcb10
Gene ID:56199
Uniprot ID:ABCBA_MOUSE
Immunogen:A synthetic peptide from aa region 300-400 of mouse ABCB10 conjugated to an immunogenic carrier protein was used as the antigen.
Immunogen Region:300-400 aa
Specificity:Specific for ABCB10.
Function ATP-dependent transporter located in the mitochondrial inner membrane that catalyzes the export of biliverdin from the mitochondrial matrix, and plays a crucial role in hemoglobin synthesis and antioxidative stress. Participates in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). Involved in the stabilization of the iron transporter mitoferrin-1/SLC25A37. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria.
Protein Name Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial
Abc-Mitochondrial Erythroid Protein
Abc-Me Protein
Atp-Binding Cassette Transporter 10
Abc Transporter 10 Protein
Database Links
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial antibody
Anti-Abc-Mitochondrial Erythroid Protein antibody
Anti-Abc-Me Protein antibody
Anti-Atp-Binding Cassette Transporter 10 antibody
Anti-Abc Transporter 10 Protein antibody
Anti-Abcb10 antibody

Information sourced from Uniprot.org