| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cholesterol transporter ABCA5 (1240-1320 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ABCA5 |
| Gene ID: |
23461 |
| Uniprot ID: |
ABCA5_HUMAN |
| Immunogen Region: |
1240-1320 aa |
| Specificity: |
ABCA5 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 1240-1320 |
| Post Translational Modifications | N-glycosylated. |
| Function | Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes. |
| Protein Name | Cholesterol Transporter Abca5Atp-Binding Cassette Sub-Family A Member 5 |
| Database Links | Reactome: R-HSA-1369062 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome MembraneLate Endosome MembraneCell MembraneLocalized At Cell Membrane Under High Cholesterol Levels |
| Alternative Antibody Names | Anti-Cholesterol Transporter Abca5 antibodyAnti-Atp-Binding Cassette Sub-Family A Member 5 antibodyAnti-ABCA5 antibodyAnti-KIAA1888 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
