| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AADAT (34-429) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AADAT |
| Gene ID: |
51166 |
| Uniprot ID: |
AADAT_HUMAN |
| Immunogen Region: |
34-429 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1). |
| Immunogen Sequence: |
PKSMISLAGGLPNPNMFPFK TAVITVENGKTIQFGEEMMK RALQYSPSAGIPELLSWLKQ LQIKLHNPPTIHYPPSQGQM DLCVTSGSQQGLCKVFEMII NPGDNVLLDEPAYSGTLQSL HPLGCNIINVASDESGIVPD SLRDILSRWKPEDAKNPQKN TPKFLYTVPNGNNPTGNSLT SERKKEIYELARKYDFLIIE DDPYYFLQFNKFRVPTFLSM DVDGRVIRADSFSKIISSG |
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - MitochondrialKat/Aadat2-Aminoadipate Aminotransferase2-Aminoadipate TransaminaseAlpha-Aminoadipate AminotransferaseAadatGlycine Transaminase AadatKynurenine Aminotransferase IiKynurenine--Glyoxylate Transaminase AadatKynurenine--Oxoglutarate Aminotransferase IiKynurenine--Oxoglutarate Transaminase 2Kynurenine--Oxoglutarate Transaminase IiMethionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial antibodyAnti-Kat/Aadat antibodyAnti-2-Aminoadipate Aminotransferase antibodyAnti-2-Aminoadipate Transaminase antibodyAnti-Alpha-Aminoadipate Aminotransferase antibodyAnti-Aadat antibodyAnti-Glycine Transaminase Aadat antibodyAnti-Kynurenine Aminotransferase Ii antibodyAnti-Kynurenine--Glyoxylate Transaminase Aadat antibodyAnti-Kynurenine--Oxoglutarate Aminotransferase Ii antibodyAnti-Kynurenine--Oxoglutarate Transaminase 2 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Ii antibodyAnti-Methionine--Glyoxylate Transaminase Aadat antibodyAnti-AADAT antibodyAnti-KAT2 antibodyAnti-KYAT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
