Anti-AADAC antibody (170-399) (STJ112402)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AADAC (170-399) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AADAC |
| Gene ID | 13 |
| Uniprot ID | AAAD_HUMAN |
| Immunogen Region | 170-399 |
| Immunogen Sequence | KKVLAKYGVNPERIGISGDS AGGNLAAAVTQQLLDDPDVK IKLKIQSLIYPALQPLDVDL PSYQENSNFLFLSKSLMVRF WSEYFTTDRSLEKAMLSRQH VPVESSHLFKFVNWSSLLPE RFIKGHVYNNPNYGSSELAK KYPGFLDVRAAPLLADDNKL RGLPLTYVITCQYDLLRDDG LMYVTRLRNTGVQVTHNHVE DGFHGAFSFLGLKISHRLIN QYIEWLKENL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 170-399 of human AADAC (NP_001077.2). |
Additional Info
| Tissue Specificity | Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder. |
| Post Translational Modifications | Glycosylation is required for enzyme activity. |
| Function | Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. |
| Protein Name | Arylacetamide Deacetylase |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Arylacetamide Deacetylase antibodyAnti-AADAC antibodyAnti-DAC antibody |
Information sourced from Uniprot.org