| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AADAC |
| Gene ID: | 13 |
| Uniprot ID: | AAAD_HUMAN |
| Immunogen Region: | 170-399 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-399 of human AADAC (NP_001077.2). |
| Immunogen Sequence: | KKVLAKYGVNPERIGISGDS AGGNLAAAVTQQLLDDPDVK IKLKIQSLIYPALQPLDVDL PSYQENSNFLFLSKSLMVRF WSEYFTTDRSLEKAMLSRQH VPVESSHLFKFVNWSSLLPE RFIKGHVYNNPNYGSSELAK KYPGFLDVRAAPLLADDNKL RGLPLTYVITCQYDLLRDDG LMYVTRLRNTGVQVTHNHVE DGFHGAFSFLGLKISHRLIN QYIEWLKENL |
| Tissue Specificity | Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder. |
| Post Translational Modifications | Glycosylation is required for enzyme activity. |
| Function | Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. |
| Protein Name | Arylacetamide Deacetylase |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Arylacetamide Deacetylase antibodyAnti-AADAC antibodyAnti-DAC antibody |
Information sourced from Uniprot.org