| Tissue Specificity | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| Post Translational Modifications | Highly glycosylated. |
| Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| Protein Name | Trophoblast Glycoprotein5t4 Oncofetal Antigen5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1Wnt-Activated Inhibitory Factor 1Waif1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Trophoblast Glycoprotein antibodyAnti-5t4 Oncofetal Antigen antibodyAnti-5t4 Oncofetal Trophoblast Glycoprotein antibodyAnti-5t4 Oncotrophoblast Glycoprotein antibodyAnti-M6p1 antibodyAnti-Wnt-Activated Inhibitory Factor 1 antibodyAnti-Waif1 antibodyAnti-TPBG antibodyAnti-5T4 antibody |
Information sourced from Uniprot.org
