Anti-2 NA, 3 NA-cyclic-nucleotide 3 NA-phosphodiesterase antibody (Full-Length) [1H10] (STJA0040807)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenFull-length recombinant human protein
General Information
| Short Description | Mouse monoclonal anti-2 NA, 3 cyclic-nucleotide 3 phosphodiesterase (Full-Length) for use in ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1H10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity-purified |
| Dilution Range | WB 1:5000-1:20000IHC 1:1000-1:5000 |
| Formulation | Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide. |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 50 ยตL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8ยฐC. After reconstitution divide into aliquot |
Target Information
| Gene Symbol | CNP |
| Gene ID | 1267 |
| Uniprot ID | CN37_HUMAN |
| Immunogen | Full-length recombinant human protein |
| Immunogen Region | Full-Length |
| Immunogen Sequence | Human |
| Specificity | Reacts with human, rat, mouse. Antibody is specific for parvalbumin and does not recognize closely related proteins calretinin and calbindin as determined by Western blotting. |
Additional Info
| Function | Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates. May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. |
| Protein Name | 2' -3'-Cyclic-Nucleotide 3'-PhosphodiesteraseCnpCnpase |
| Database Links | |
| Cellular Localisation | MembraneLipid-AnchorMelanosomeFirmly Bound To Membrane Structures Of Brain White Matter |
| Alternative Antibody Names | Anti-2' -3'-Cyclic-Nucleotide 3'-Phosphodiesterase antibodyAnti-Cnp antibodyAnti-Cnpase antibodyAnti-CNP antibody |
Information sourced from Uniprot.org