| Short Description : | Mouse monoclonal anti-14-3-3 eta for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 5F2F1E11 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | YWHAH |
| Gene ID: | 7533 |
| Uniprot ID: | 1433F_HUMAN |
| Immunogen: | Antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human 14-3-3 Eta. |
| Tissue Specificity | Expressed mainly in the brain and present in other tissues albeit at lower levels. |
| Post Translational Modifications | Phosphorylated on Ser-59 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. |
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
| Protein Name | 14-3-3 Protein EtaProtein As1 |
| Database Links | Reactome: R-HSA-111447Reactome: R-HSA-1445148Reactome: R-HSA-5625740Reactome: R-HSA-5628897Reactome: R-HSA-75035Reactome: R-HSA-9735871Reactome: R-HSA-9755779Reactome: R-HSA-9856649 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-14-3-3 Protein Eta antibodyAnti-Protein As1 antibodyAnti-YWHAH antibodyAnti-YWHA1 antibody |
Information sourced from Uniprot.org
