| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
TUFM Blocking Peptide for STJ506049 is synthetically produced from the 325-375 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
TUFM |
| Gene ID: |
7284 |
| Uniprot ID: |
EFTU_HUMAN |
| Immunogen Region: |
325-375 |
| Specificity: |
This blocking peptide is recommended for use in combination with TUFM antibody, STJ506049 |
| Immunogen: |
Synthetic peptide taken within amino acid region 325-375 on human Elongation factor Tu, mitochondrial. |
| Function | Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. |
| Peptide Name | Elongation Factor Tu - MitochondrialEf-TuP43 |
| Database Links | Reactome: R-HSA-5389840Reactome: R-HSA-9754560 |
| Cellular Localisation | Mitochondrion |
| Alternative Peptide Names | Elongation Factor Tu - Mitochondrial proteinEf-Tu proteinP43 proteinTUFM protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
