| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | TOMM7 Positive Control for STJ503355 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | TOMM7 |
| Gene ID: | 54543 |
| Uniprot ID: | TOM7_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with TOMM7 antibody STJ503355. |
| Function | Required for assembly and stability of the TOM complex. Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria. |
| Peptide Name | Mitochondrial Import Receptor Subunit Tom7 HomologTranslocase Of Outer Membrane 7 Kda Subunit Homolog |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Mitochondrial Import Receptor Subunit Tom7 Homolog proteinTranslocase Of Outer Membrane 7 Kda Subunit Homolog proteinTOMM7 proteinTOM7 proteinTOMM07 proteinAD-014 protein |
Information sourced from Uniprot.org