| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
TMC2 Positive Control for STJ503321 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:2, 500-1:5, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
TMC2 |
| Gene ID: |
117532 |
| Uniprot ID: |
TMC2_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with TMC2 antibody STJ503321. |
| Immunogen: |
Purified Transmembrane channel-like protein 2. |
| Tissue Specificity | Detected in fetal cochlea. |
| Function | Probable ion channel required for the normal function of cochlear hair cells. Component of the hair cell's mechanotransduction (MET) machinery. Involved in mechanosensitive responses of the hair cells. |
| Peptide Name | Transmembrane Channel-Like Protein 2Transmembrane Cochlear-Expressed Protein 2 |
| Database Links | Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Stereocilia Of The Cochlear Hair Cells |
| Alternative Peptide Names | Transmembrane Channel-Like Protein 2 proteinTransmembrane Cochlear-Expressed Protein 2 proteinTMC2 proteinC20orf145 proteinUNQ907 proteinPRO1928 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
