| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
TLR13 Blocking Peptide for STJ503294 is synthetically produced from the 400-480 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Tlr13 |
| Gene ID: |
279572 |
| Uniprot ID: |
TLR13_MOUSE |
| Immunogen Region: |
400-480 |
| Specificity: |
This blocking peptide is recommended for use in combination with TLR13 antibody, STJ503294 |
| Immunogen: |
Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein. |
| Function | Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus.however, these data require additional evidences. |
| Peptide Name | Toll-Like Receptor 13 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Toll-Like Receptor 13 proteinTlr13 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
