| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | TLR10 Positive Control for STJ503273 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | TLR10 |
| Gene ID: | 81793 |
| Uniprot ID: | TLR10_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with TLR10 antibody STJ503273. |
| Tissue Specificity | Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| Peptide Name | Toll-Like Receptor 10Cd Antigen Cd290 |
| Database Links | Reactome: R-HSA-168142Reactome: R-HSA-5603037Reactome: R-HSA-975871 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Toll-Like Receptor 10 proteinCd Antigen Cd290 proteinTLR10 proteinUNQ315 proteinPRO358 protein |
Information sourced from Uniprot.org
