| Post Translational Modifications | Phosphorylated on Tyr residues quickly after TCR stimulation. |
| Function | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
| Peptide Name | Protein ThemisThymocyte-Expressed Molecule Involved In Selection |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Peptide Names | Protein Themis proteinThymocyte-Expressed Molecule Involved In Selection proteinTHEMIS proteinC6orf190 proteinC6orf207 protein |
Information sourced from Uniprot.org
