| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
SRPX2 Positive Control for STJ503136 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
SRPX2 |
| Gene ID: |
27286 |
| Uniprot ID: |
SRPX2_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with SRPX2 antibody STJ503136. |
| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa. |
| Post Translational Modifications | Contains chondroitin sulfate chains. |
| Function | Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. |
| Peptide Name | Sushi Repeat-Containing Protein Srpx2Sushi-Repeat Protein Upregulated In Leukemia |
| Cellular Localisation | SecretedCytoplasmCell SurfaceSynapse |
| Alternative Peptide Names | Sushi Repeat-Containing Protein Srpx2 proteinSushi-Repeat Protein Upregulated In Leukemia proteinSRPX2 proteinSRPUL protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
