| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | SLC9A3 Blocking Peptide for STJ506227 is synthetically produced from the 590-640 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SLC9A3 |
| Gene ID: | 6550 |
| Uniprot ID: | SL9A3_HUMAN |
| Immunogen Region: | 590-640 |
| Specificity: | This blocking peptide is recommended for use in combination with SLC9A3 antibody, STJ506227 |
| Immunogen: | Synthetic peptide corresponding to amino acids within region 590-640 on human SLC9A3 protein. |
| Function | Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation. |
| Peptide Name | Sodium/Hydrogen Exchanger 3 Na(+/H(+ Exchanger 3 Nhe-3 Solute Carrier Family 9 Member 3 |
| Database Links | Reactome: R-HSA-425986 |
| Cellular Localisation | Apical Cell Membrane Multi-Pass Membrane Protein Cell Membrane Recycling Endosome Membrane Early Endosome Membrane In Intestinal Epithelial Cells Localizes To The Ileal Brush Border Phosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell Membrane Angiotensin-2 Enhances Apical Expression |
| Alternative Peptide Names | Sodium/Hydrogen Exchanger 3 protein Na(+/H(+ Exchanger 3 protein Nhe-3 protein Solute Carrier Family 9 Member 3 protein SLC9A3 protein NHE3 protein |
Information sourced from Uniprot.org