| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | SHISA9 Positive Control for STJ500557 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Shisa9 |
| Gene ID: | 72555 |
| Uniprot ID: | SHSA9_MOUSE |
| Specificity: | This is positive control is recommended for use in combination with SHISA9 antibody STJ500557. |
| Tissue Specificity | Brain-specific. Mainly expressed in neurons, including in hippocampus, cerebral cortex, striatum, thalamus, olfactory bulb and cerebellum. Expressed in most brain structures during embryonic and postnatal development. |
| Function | Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. |
| Peptide Name | Protein Shisa-9Cystine-Knot Ampar Modulating Protein Of 44 KdaCkamp44 |
| Cellular Localisation | Cell ProjectionDendritic Spine MembraneSingle-Pass Type I Membrane ProteinSynapse |
| Alternative Peptide Names | Protein Shisa-9 proteinCystine-Knot Ampar Modulating Protein Of 44 Kda proteinCkamp44 proteinShisa9 protein |
Information sourced from Uniprot.org