| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | SHISA9 Blocking Peptide for STJ500557 is synthetically produced from the 250-300 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Shisa9 |
| Gene ID: | 72555 |
| Uniprot ID: | SHSA9_MOUSE |
| Immunogen Region: | 250-300 |
| Specificity: | This blocking peptide is recommended for use in combination with SHISA9 antibody, STJ500557 |
| Immunogen: | Synthetic peptide taken within amino acid region 250-300 on CKAMP44a protein. |
| Tissue Specificity | Brain-specific. Mainly expressed in neurons, including in hippocampus, cerebral cortex, striatum, thalamus, olfactory bulb and cerebellum. Expressed in most brain structures during embryonic and postnatal development. |
| Function | Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. |
| Peptide Name | Protein Shisa-9Cystine-Knot Ampar Modulating Protein Of 44 KdaCkamp44 |
| Cellular Localisation | Cell ProjectionDendritic Spine MembraneSingle-Pass Type I Membrane ProteinSynapse |
| Alternative Peptide Names | Protein Shisa-9 proteinCystine-Knot Ampar Modulating Protein Of 44 Kda proteinCkamp44 proteinShisa9 protein |
Information sourced from Uniprot.org