| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
SHC Positive Control for STJ502999 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Shc3 |
| Gene ID: |
20418 |
| Uniprot ID: |
SHC3_MOUSE |
| Specificity: |
This is positive control is recommended for use in combination with SHC antibody STJ502999. |
| Tissue Specificity | Predominantly expressed in the adult brain. |
| Post Translational Modifications | Tyrosine phosphorylated. |
| Function | Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. |
| Peptide Name | Shc-Transforming Protein 3Neuronal ShcN-ShcShc-Transforming Protein CSrc Homology 2 Domain-Containing-Transforming Protein C3Sh2 Domain Protein C3 |
| Database Links | Reactome: R-MMU-167044Reactome: -MMU-5673001Reactome: -MMU-8853659 |
| Alternative Peptide Names | Shc-Transforming Protein 3 proteinNeuronal Shc proteinN-Shc proteinShc-Transforming Protein C proteinSrc Homology 2 Domain-Containing-Transforming Protein C3 proteinSh2 Domain Protein C3 proteinShc3 proteinNshc proteinShcC protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
