SGLT2 Positive Control peptide (STJ505144)

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STJ505144-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : SGLT2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC5A2
Gene ID: 6524
Uniprot ID: SC5A2_HUMAN
Function Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Unlike SLC5A1/SGLT1, requires the auxiliary protein PDZK1IP1/MAP17 for full transporter activity. Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney.
Peptide Name Sodium/Glucose Cotransporter 2
Na(+/Glucose Cotransporter 2
Low Affinity Sodium-Glucose Cotransporter
Solute Carrier Family 5 Member 2
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-5658208
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Sodium/Glucose Cotransporter 2 protein
Na(+/Glucose Cotransporter 2 protein
Low Affinity Sodium-Glucose Cotransporter protein
Solute Carrier Family 5 Member 2 protein
SLC5A2 protein
SGLT2 protein

Information sourced from Uniprot.org

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