Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
Peptide Name | Secreted Frizzled-Related Protein 2Frp-2Sfrp-2Secreted Apoptosis-Related Protein 1Sarp-1 |
Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
Cellular Localisation | Secreted |
Alternative Peptide Names | Secreted Frizzled-Related Protein 2 proteinFrp-2 proteinSfrp-2 proteinSecreted Apoptosis-Related Protein 1 proteinSarp-1 proteinSFRP2 proteinFRP2 proteinSARP1 proteinFKSG12 proteinUNQ361 proteinPRO697 protein |
Information sourced from Uniprot.org