Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
SEC23 Blocking Peptide is synthetically produced from the 700-765 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SEC23A |
Gene ID: |
10484 |
Uniprot ID: |
SC23A_HUMAN |
Immunogen Region: |
700-765 |
Immunogen: |
Synthetic peptide taken within amino acid region 700-765 on human SEC23A protein. |
Tissue Specificity | Ubiquitously expressed. |
Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane. |
Peptide Name | Protein Transport Protein Sec23aHsec23aSec23-Related Protein A |
Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytoplasmCytosolEnriched At Endoplasmic Reticulum Exit SitesAlso Known As Transitional Endoplasmic Reticulum (Ter) |
Alternative Peptide Names | Protein Transport Protein Sec23a proteinHsec23a proteinSec23-Related Protein A proteinSEC23A protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance