| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | RHBDF2 Positive Control for STJ506169 is synthetically produced from the 800-850 sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | RHBDF2 |
| Gene ID: | 79651 |
| Uniprot ID: | RHDF2_HUMAN |
| Immunogen Region: | 800-850 |
| Specificity: | This is positive control is recommended for use in combination with RHBDF2 antibody STJ506169. |
| Immunogen: | Synthetic peptide taken within amino aid region 800-850 on human Inactive rhomboid protein 2. |
| Tissue Specificity | Found in the epidermis and esophageal epithelium. |
| Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
| Peptide Name | Inactive Rhomboid Protein 2Irhom2Rhomboid 5 Homolog 2Rhomboid Family Member 2Rhomboid Veinlet-Like Protein 5Rhomboid Veinlet-Like Protein 6 |
| Database Links | Reactome: R-HSA-9662834 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Peptide Names | Inactive Rhomboid Protein 2 proteinIrhom2 proteinRhomboid 5 Homolog 2 proteinRhomboid Family Member 2 proteinRhomboid Veinlet-Like Protein 5 proteinRhomboid Veinlet-Like Protein 6 proteinRHBDF2 proteinIRHOM2 proteinRHBDL5 proteinRHBDL6 protein |
Information sourced from Uniprot.org