| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Relaxin 1 Positive Control for STJ502816 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Rxfp1 |
| Gene ID: | 295144 |
| Uniprot ID: | RXFP1_RAT |
| Specificity: | This is positive control is recommended for use in combination with Relaxin 1 antibody STJ502816. |
| Tissue Specificity | Detected in brain cortex, and at low levels in testis. |
| Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
| Peptide Name | Relaxin Receptor 1Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7Relaxin Family Peptide Receptor 1 |
| Database Links | Reactome: R-RNO-444821 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Relaxin Receptor 1 proteinLeucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 proteinRelaxin Family Peptide Receptor 1 proteinRxfp1 proteinLgr7 protein |
Information sourced from Uniprot.org