| Tissue Specificity | |
| Post Translational Modifications | Glycosylated. Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation. |
| Function | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. |
| Protein Name | Thyrotropin ReceptorThyroid-Stimulating Hormone ReceptorTsh-R |
| Database Links | Reactome: R-RNO-375281 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative ELISA Names | Thyrotropin Receptor ELISA kitThyroid-Stimulating Hormone Receptor ELISA kitTsh-R ELISA kitTshr ELISA kit |
| output | |
Information sourced from Uniprot.org