Rat SGLT2 (Sodium/Glucose Cotransporter 2) Sandwich ELISA Kit (STJE0012139)
SPECIFICATIONS
General Information
| Short Description | This SGLT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.051ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Slc5a2 |
| Gene ID | 64522 |
| Uniprot ID | SC5A2_RAT |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Kidney, in proximal tubule S1 segments. |
| Post Translational Modifications | Glycosylated at a single site. |
| Function | Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Unlike SLC5A1/SGLT1, requires the auxiliary protein PDZK1IP1/MAP17 for full transporter activity. Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney. |
| Protein Name | Sodium/Glucose Cotransporter 2Na(+/Glucose Cotransporter 2Low Affinity Sodium-Glucose CotransporterSolute Carrier Family 5 Member 2 |
| Database Links | Reactome: R-RNO-189200 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Sodium/Glucose Cotransporter 2 ELISA kitNa(+/Glucose Cotransporter 2 ELISA kitLow Affinity Sodium-Glucose Cotransporter ELISA kitSolute Carrier Family 5 Member 2 ELISA kitSlc5a2 ELISA kitSglt2 ELISA kit |
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Information sourced from Uniprot.org