Rat S100A4 (S100 Calcium Binding Protein A4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018368)

Rat S100A4 (S100 Calcium Binding Protein A4) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018368)

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STJE0018368
£518.50 - £712.50
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 34pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description : This S100A4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: S100a4
Gene ID: 24615
Uniprot ID: S10A4_RAT
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Modulates also the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors.
Protein Name Protein S100-A4
Metastasin
Nerve Growth Factor-Induced Protein 42a
P9k
Placental Calcium-Binding Protein
S100 Calcium-Binding Protein A4
Database Links
Cellular Localisation Secreted
Nucleus
Cytoplasm
Alternative ELISA Names Protein S100-A4 ELISA kit
Metastasin ELISA kit
Nerve Growth Factor-Induced Protein 42a ELISA kit
P9k ELISA kit
Placental Calcium-Binding Protein ELISA kit
S100 Calcium-Binding Protein A4 ELISA kit
S100a4 ELISA kit
output

Information sourced from Uniprot.org

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