Rat PYGL (Glycogen Phosphorylase, Liver) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018174)

Rat PYGL (Glycogen Phosphorylase, Liver) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018174)

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STJE0018174
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.56ng/mL
Detection Limit: 1.56-100ng/mL
Short Description : This PYGL Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Pygl
Gene ID: 64035
Uniprot ID: PYGL_RAT
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Acetylation, which is up-regulated by glucose and insulin and down-regulated by glucagon, inhibits the glycogen phosphorylase activity by promoting PPP1R3B-mediated recruitment of phosphatase PP1 and Ser-15 dephosphorylation. Phosphorylation at Ser-15 converts inactive phosphorylase b into active phosphorylase a. Dephosphorylation of Ser-15 by phosphatase PP1 inactivates the enzyme.
Function Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Protein Name Glycogen Phosphorylase - Liver Form
Database Links Reactome: R-RNO-6798695
Reactome: -RNO-70221
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Glycogen Phosphorylase - Liver Form ELISA kit
Pygl ELISA kit
Lgp ELISA kit
output

Information sourced from Uniprot.org

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