| Applications: | ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.057ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This OSTN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Ostn |
| Gene ID: | 360730 |
| Uniprot ID: | OSTN_RAT |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in skeletal muscle. Also expressed in leg tendons/ligaments and osteoblasts. In long bones and teeth, present in knee joint and periodontal ligaments (at protein level). |
| Post Translational Modifications | |
| Function | Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. |
| Protein Name | Osteocrin Musclin Cleaved Into - Processed Osteocrin |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Osteocrin ELISA kit Musclin Cleaved Into - Processed Osteocrin ELISA kit Ostn ELISA kit |
| output |
Information sourced from Uniprot.org
