| Tissue Specificity | Expressed in brain, placenta, kidney, neuron and skeletal muscle. Expressed in the developing eye, pituitary and brain. |
| Post Translational Modifications | Glycosylated. |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides. |
| Protein Name | Patatin-Like Phospholipase Domain-Containing Protein 6Neuropathy Target Esterase |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative ELISA Names | Patatin-Like Phospholipase Domain-Containing Protein 6 ELISA kitNeuropathy Target Esterase ELISA kitPNPLA6 ELISA kitNTE ELISA kit |
| output | |
Information sourced from Uniprot.org