Tissue Specificity | Expressed in brain, placenta, kidney, neuron and skeletal muscle. Expressed in the developing eye, pituitary and brain. |
Post Translational Modifications | Glycosylated. |
Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides. |
Protein Name | Patatin-Like Phospholipase Domain-Containing Protein 6Neuropathy Target Esterase |
Database Links | Reactome: R-HSA-6814848 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
Alternative ELISA Names | Patatin-Like Phospholipase Domain-Containing Protein 6 ELISA kitNeuropathy Target Esterase ELISA kitPNPLA6 ELISA kitNTE ELISA kit |
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Information sourced from Uniprot.org