Tissue Specificity | Expressed at high levels in the lung and testis, at intermediate levels in the kidney, heart and brain and at low levels in the muscle and liver. |
Post Translational Modifications | Phosphorylation enhances DNA binding. |
Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
Protein Name | Nuclear Respiratory Factor 1Nrf-1Alpha Palindromic-Binding ProteinAlpha-Pal |
Database Links | |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Nuclear Respiratory Factor 1 ELISA kitNrf-1 ELISA kitAlpha Palindromic-Binding Protein ELISA kitAlpha-Pal ELISA kitNrf1 ELISA kit |
output | |
Information sourced from Uniprot.org