| Post Translational Modifications | Hydroxylated on lysine and proline residues within the collagen-like domain. O-glycosylated. O-linked glycans on hydroxylysine residues consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups. |
| Function | Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |
| Protein Name | Mannose-Binding Protein AMbp-AMannan-Binding Protein |
| Cellular Localisation | SecretedLong Retention Times In The Endoplasmic Reticulum And The Golgi Apparatus That Have Been Observed In Former Studies May Reflect The Abnormal Physiology Of The Hepatoma Cells Used |
| Alternative Protein Names | Mannose-Binding Protein A proteinMbp-A proteinMannan-Binding Protein proteinMbl1 protein |
Information sourced from Uniprot.org
