Tissue Specificity | Most abundant in heart tissue where it is found predominantly in atria. Also found in brain, kidney, liver, spleen, lung and thymus. |
Post Translational Modifications | |
Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. |
Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 4Girk-4Cardiac Inward RectifierCirHeart Katp ChannelInward Rectifier K(+ Channel Kir3.4Katp-1Potassium Channel - Inwardly Rectifying Subfamily J Member 5 |
Database Links | Reactome: R-RNO-1296041Reactome: -RNO-997272 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | G Protein-Activated Inward Rectifier Potassium Channel 4 ELISA kitGirk-4 ELISA kitCardiac Inward Rectifier ELISA kitCir ELISA kitHeart Katp Channel ELISA kitInward Rectifier K(+ Channel Kir3.4 ELISA kitKatp-1 ELISA kitPotassium Channel - Inwardly Rectifying Subfamily J Member 5 ELISA kitKcnj5 ELISA kitGirk4 ELISA kit |
output | |
Information sourced from Uniprot.org