Tissue Specificity | |
Post Translational Modifications | Phosphorylated upon ligand binding.which is required for desensitization. |
Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Gro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BCd Antigen Cd182 |
Database Links | Reactome: R-RNO-380108Reactome: -RNO-418594Reactome: -RNO-6798695 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | C-X-C Chemokine Receptor Type 2 ELISA kitCxc-R2 ELISA kitCxcr-2 ELISA kitGro/Mgsa Receptor ELISA kitHigh Affinity Interleukin-8 Receptor B ELISA kitIl-8r B ELISA kitCd Antigen Cd182 ELISA kitCxcr2 ELISA kitIl8rb ELISA kit |
output | |
Information sourced from Uniprot.org