Applications: | ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.113ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description : | This ICAM1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Icam1 |
Gene ID: | 25464 |
Uniprot ID: | ICAM1_RAT |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
Protein Name | Intercellular Adhesion Molecule 1Icam-1Cd Antigen Cd54 |
Database Links | Reactome: R-RNO-198933Reactome: -RNO-216083 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Intercellular Adhesion Molecule 1 ELISA kitIcam-1 ELISA kitCd Antigen Cd54 ELISA kitIcam1 ELISA kitIcam-1 ELISA kit |
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Information sourced from Uniprot.org