| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Rat GSN-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Gsn |
| Gene ID: | 296654 |
| Uniprot ID: | GELS_RAT |
| Immunogen Region: | Glu53-Asn393 |
| Immunogen: | Rattus norvegicus (Rat) |
| Function | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. |
| Protein Name | GelsolinActin-Depolymerizing FactorAdfBrevin |
| Database Links | Reactome: R-RNO-264870Reactome: -RNO-6798695 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmCytoskeletonA Cytoplasmic Form May Also Exist |
| Alternative Protein Names | Gelsolin proteinActin-Depolymerizing Factor proteinAdf proteinBrevin proteinGsn protein |
Information sourced from Uniprot.org