Tissue Specificity | |
Post Translational Modifications | |
Function | Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. |
Protein Name | Galectin-1Gal-114 Kda LectinBeta-Galactoside-Binding Lectin L-14-IGalaptinLactose-Binding Lectin 1Lectin Galactoside-Binding Soluble 1Rl 14.5S-Lac Lectin 1 |
Database Links | Reactome: R-RNO-381426Reactome: -RNO-8957275 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCytoplasmCan Be SecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
Alternative ELISA Names | Galectin-1 ELISA kitGal-1 ELISA kit14 Kda Lectin ELISA kitBeta-Galactoside-Binding Lectin L-14-I ELISA kitGalaptin ELISA kitLactose-Binding Lectin 1 ELISA kitLectin Galactoside-Binding Soluble 1 ELISA kitRl 14.5 ELISA kitS-Lac Lectin 1 ELISA kitLgals1 ELISA kit |
output | |
Information sourced from Uniprot.org