Tissue Specificity | |
Post Translational Modifications | |
Function | Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
Protein Name | Ficolin-1Collagen/Fibrinogen Domain-Containing Protein 1Ficolin-AFicolin-AlphaM-Ficolin |
Database Links | |
Cellular Localisation | SecretedCell MembranePeripheral Membrane ProteinExtracellular SideFound On The Monocyte And Granulocyte Surface |
Alternative ELISA Names | Ficolin-1 ELISA kitCollagen/Fibrinogen Domain-Containing Protein 1 ELISA kitFicolin-A ELISA kitFicolin-Alpha ELISA kitM-Ficolin ELISA kitFcn1 ELISA kitFcna ELISA kit |
output | |
Information sourced from Uniprot.org